Prototheca infections were mainly seen in animals, while
In humans, prototheca mostly cause cutaneous infections, 25% cases were
olecranon bursitis, and systemic infection including Chronic peritonitis in
peritoneal dialysis patients, secondary infection of AIDS or Chronic
meningitis, etc., were rare disseminated diseases. Davies et al. reported thefirst human infection with this specie in 1964 and since then sporadic cases ofprototheca infection were described in different parts of the world. And then,
the first descript of prototheca meningitis was reported by Kaminski in 1992.
In 1996, the second case of meningitis was described in Japan and the infection
persisted for 6 years. In China, the first detailed report of meningitis was
caused by P. wickerhamii which occurred in 2007 and was successfully treated
with AMB and ITZ. And Prototheca wickerhamii as a cause of neuroinfection in a
child with congenital hydrocephalus was the first case of human protothecosis
in Poland. To our knowledge, we reported the 5th case of human prototheca
meningitis in the literature.
A 23 year old young man was
admitted to department of infectious disease of the third affiliated hospital
of Sun Yat-sen university, complaining of fever, headache and vomiting. Beforeadmission, he had been diagnosed as tuberculous meningitis. After taking
chemical therapy with antituberculous drugs combined with adrenocortical hormones for
two months, his condition deteriorated.
No comments:
Post a Comment