Cancer is a malignant neoplasm defined as an abnormal growth and division of cells. Molecular mechanisms of cancer predicted that there are two broad categories of genes such as proto-oncogenes and tumor suppressor genes control mitotic cell division. Tumor suppressor genes inhibit cell division, survival, or other properties of cancer cells. Oncogenes are the mutations of normal host genes which are proto-oncogene. Proto-oncogenes are good genes that normally control the essential cell functions such as cell proliferation and differentiation through signal transduction.
Abnormal signal transduction can lead to cancer which engulfs the brain, blood, lymph nodes, lungs, bone, and every other bodily organ, part, or system. But why is heart rarely affected by the cancer? This answer is much more silent yet and literature on heart cancer is quite limited. So it is very crucial topic for the genomic scientist and pharmacologist to explore the reason behind this. Primary cardiac tumor was scarce whereas malignant heart tumors also known as angiosarcoma or cardiac sarcoma are extremely rare. A sarcoma is a type of tumor that originates in the soft tissues of the body. A type of rhabdomyosarcoma occurs in the cardiac muscle tissues
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